Determination of 18 ?-Glycyrrhetinic Acid in Glycyrrhiza glabra L. Extract by HPLC

نویسندگان

  • F Naghibi
  • M Mosaddegh
  • N Nader
  • S Esmaeili
چکیده مقاله:

A high performance liquid chromatography method was studied for determination of 18 ?-glycyrrhetinic acid in Glycyrrhiza glabra L. (licorice) extract. The operating condition were C-18 reversed phase column (VP-ODS, (250×4.6 mm, 5 mm)) at room temperature, acetonitril/phosphoric acid (3/1) as mobile phase, at flow rate of 0.6ml/min (0-8min), 0.4ml/min (8-20min) and UV detection at 230 nm. The recoveries were %99.60-%102.81 with relative standard deviation between %0.01-%1.58. The relative standard deviation of the repeatability test was %2.96. The method is simple, rapid, safe, accurate, economical and useful for standardization of the licorice products.

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determination of 18 ?-glycyrrhetinic acid in glycyrrhiza glabra l. extract by hplc

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عنوان ژورنال

دوره Volume 5  شماره Number 2

صفحات  137- 141

تاریخ انتشار 2010-11-20

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